Wellness Hub: Understanding COVID-19 Transmission through Implementing and Evaluating an Intervention to Support Wellness, Infection Prevention and Control, Vaccine Uptake, and Other Wraparound Care Needs in Long-term Care and Retirement Homes
The purpose of this study is to:
* Estimate the change in prevalence of, as well as correlates of, prior SARS-CoV-2 infection in of long-term care home (LTCH) and retirement home (RH) settings,
* Estimate factors associated with infection and prevention of infection in these settings,
* Understand immune correlates of infection and disease in a diverse population of LTCH/RH residents, their families, LTCH/RH staff, and their household members,
* Use an integrated knowledge translation (iKT) approach to implement and evaluate the impact of Wellness Hub in preventing infections across these four populations, and
* Understand barriers and facilitators to implementing dried blood spot (DBS) and saliva testing in LTCH/RH residents, their families, LTCH/RH staff, and their household members to inform large-scale implementation of screening and surveillance.
The research objectives are to:
* Estimate the population-specific prevalence and correlates of prior SARS-CoV-2 infection using DBS testing among four populations (LTCH/RH residents and their families/caregivers, as well as LTCH/RH staff and their household members) across 72 LTCH/RH across Ontario.
* Understand COVID-19 immune correlates of protection (including vaccine) and of disease.
* Implement Wellness Hub at 48 LTCH/RHs in Ontario, an infection prevention and wellness intervention, which includes onsite saliva testing for symptomatic or high-risk exposure LTCH/RH staff and their household members and residents’ essential care partners & SARS-CoV-2 wastewater (WW) testing at LTCH and communities in the Greater Toronto Area (GTA) and Ottawa regions (sub-objective 3a).
* Evaluate the impact of the Wellness Hub bundle on incidence of PCR-confirmed SARS-CoV-2 infections among LTCH/RH residents, hospitalizations among LTCH/RH residents, re-infection among LTCH/RH staff and residents, correlates of risk over time among LTCH/RH staff and Wellness Hub implementation outcomes.
* Explore the barriers and facilitators to implementing DBS and saliva testing among a sample of LTCH/RH staff, staff household members, and families of LTCH/RH residents to inform future large-scale implementation of screening and surveillance.
Overview
- Acronym
- WH
- Website
- WH
- Investigators
-
- Contacts
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General Design
- Study design
- Cross-sectional
- Start - End Year
- 2020 - 2022
- General Information on Follow Up (profile, frequency)
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The Wellness Hub intervention is implemented at sites for up to 12 months. DBS samples and demographic questionnaires are collected at baseline (month 1) and month 9.
- Recruitment Target
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- Individuals
- Number of Participants
- 20,448
- Number of Participants with Biological Samples
- 20,448
- Supplementary information about number of participants
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Participants will be recruited on a rolling basis.
- Supplementary Information
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This is a serial cross-sectional with nested cohort study.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
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Our data management plan aligns with the overarching data governance plan of the COVID-19 Immunity Task Force (funder) and with the Framework for Researchers that was prepared by the TriCouncil Agencies.
The CITF will share data with researchers in Canada and internationally so as to understand the science underlying COVID-19 immunity, COVID-19 infection rates in the Canadian population, and study-related health outcomes. In the future, this data may be shared via the cloud, both nationally and internationally. Other researchers internationally will be able to submit a request to the CITF to receive access to their data through their data access committee. The CITF data access committee will employ a rigorous checklist to ensure that these external requests follow all necessary ethical and privacy protocols prior to approval.
Additionally, other researchers can submit requests to the study team (NPI) to access the de-identified, anonymized data upon publication submission as per Tri-Council requirements and in keeping with the joint statement on data sharing during public health emergencies; in some cases (e.g. retrieval of specimens) fees may be charged to users to recover incurred costs.
Timeline
Populations
WH - LTCH/RH Residents
The population is composed of people residing in 72 selected long-term care and retirement homes (LTCH/RH) sites in Ontario, Canada.
Selection Criteria
- Countries
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- Canada
- Canadian Provinces
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- Ontario
- Ethnic Origin
-
- Not Indigenous
- Health Status
-
- Individuals who have blood clotting conditions (e.g., hemophilia) or individuals who have experienced fainting or vomiting due to a finger prick or the sight of blood will be discouraged from completing the DBS test.
- Other Criteria
- English or French-speaking
Sources of Recruitment
- Specific Population
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- Clinic patients
Sample Size
- Number of Participants
- 2,520
- Number of Participants with Biological Samples
- 2,520
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | WH - LTCH/RH Residents - Baseline |
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|
2021 (May) | 2021 (October) |
| 1 | WH - LTCH/RH Residents - Follow-up |
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2022 (January) | 2022 (June) |
WH - LTCH/RH Residents’ Families/Caregivers
The population is composed of essential care partners/family members/caregivers of residents of 72 selected long-term care and retirement homes (LTCH/RH) sites in Ontario, Canada.
Selection Criteria
- Countries
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- Canada
- Canadian Provinces
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- Ontario
- Ethnic Origin
-
- Not Indigenous
- Health Status
-
- Individuals who have blood clotting conditions (e.g., hemophilia) or individuals who have experienced fainting or vomiting due to a finger prick or the sight of blood will be discouraged from completing the DBS test.
- Other Criteria
- English or French-speaking
Sources of Recruitment
- Specific Population
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- Other specific population : Family members or caregivers of residents in LTCH/RH
Sample Size
- Number of Participants
- 5,976
- Number of Participants with Biological Samples
- 5,976
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | WH - LTCH/RH Residents’ Families/Caregivers - Baseline |
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|
2021 (May) | 2021 (October) |
| 2 | WH - LTCH/RH Residents’ Families/Caregivers - Low-risk Intervention |
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|
2021 (March) | 2022 (March) |
| 3 | WH - LTCH/RH Residents’ Families/Caregivers - Low-risk Control |
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2021 (March) | 2022 (March) |
| 4 | WH - LTCH/RH Residents’ Families/Caregivers - High-risk Intervention |
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2021 (March) | 2022 (March) |
| 5 | WH - LTCH/RH Residents’ Families/Caregivers - High-risk Control |
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2021 (March) | 2022 (March) |
| 6 | WH - LTCH/RH Residents’ Families/Caregivers - Follow-up |
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|
2022 (January) | 2022 (June) |
WH - LTCH/RH Staff
The population is composed of staff members in 72 selected long-term care and retirement homes (LTCH/RH) sites in Ontario, Canada.
Selection Criteria
- Minimum age
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18
- Countries
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- Canada
- Canadian Provinces
-
- Ontario
- Ethnic Origin
-
- Not Indigenous
- Health Status
-
- Individuals who have blood clotting conditions (e.g., hemophilia) or individuals who have experienced fainting or vomiting due to a finger prick or the sight of blood will be discouraged from completing the DBS test.
- Other Criteria
- English or French-speaking
Sources of Recruitment
- Specific Population
-
- Other specific population : LTCH/RH Staff
Sample Size
- Number of Participants
- 5,976
- Number of Participants with Biological Samples
- 5,976
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | WH - LTCH/RH Staff - Baseline |
|
|
2021 (May) | 2021 (October) |
| 2 | WH - LTCH/RH Staff - Low-risk Intervention |
|
|
2021 (March) | 2022 (March) |
| 3 | WH - LTCH/RH Staff - Low-risk Control |
|
|
2021 (March) | 2022 (March) |
| 4 | WH - LTCH/RH Staff - High-risk Intervention |
|
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2021 (March) | 2022 (March) |
| 5 | WH - LTCH/RH Staff - High-risk Control |
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2021 (March) | 2022 (March) |
| 6 | WH - LTCH/RH Staff - Follow-up |
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2022 (January) | 2022 (June) |
| 7 | WH - LTCH/RH Staff - Nested case study |
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2021 (May) | 2022 (May) |
WH - LTCH/RH Staff Household Members
The population is composed of staff's household members (someone that the LTCH staff shares a household with on average three nights per week) in 72 selected long-term care and retirement homes (LTCH/RH) sites in Ontario, Canada.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Ontario
- Ethnic Origin
-
- Not Indigenous
- Health Status
-
- Individuals who have blood clotting conditions (e.g., hemophilia) or individuals who have experienced fainting or vomiting due to a finger prick or the sight of blood will be discouraged from completing the DBS test.
- Other Criteria
- English or French-speaking
Sources of Recruitment
- Specific Population
-
- Other specific population : Household members of staff in LTCH/RH
Sample Size
- Number of Participants
- 5,976
- Number of Participants with Biological Samples
- 5,976
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | WH - LTCH/RH Staff Household Members - Baseline |
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|
2021 (March) | 2021 (October) |
| 2 | WH - LTCH/RH Staff Household Members - Low-risk Intervention |
|
|
2021 (March) | 2022 (March) |
| 3 | WH - LTCH/RH Staff Household Members - Low-risk Control |
|
|
2021 (March) | 2022 (March) |
| 4 | WH - LTCH/RH Staff Household Members - High-risk Intervention |
|
|
2021 (March) | 2022 (March) |
| 5 | WH - LTCH/RH Staff Household Members - High-risk Control |
|
|
2021 (March) | 2022 (March) |
| 6 | WH - LTCH/RH Staff Household Members - Follow-up |
|
|
2022 (January) | 2022 (June) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-02-27T15:27:47.463