Prospective collection and biobanking of samples from certain cancers
The aim of U-CAN cohort are:
* To generate an internationally competitive high-quality longitudinal biobank of selected cancer cases.
* To create a database of well-structured multidisciplinary clinical information on a large number of patients from defined geographical areas.
* To be a substrate for cutting edge translational and clinical cancer research.
Overview
- Acronym
- U-CAN
- Website
- U-CAN
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2010 -
- General Information on Follow Up (profile, frequency)
-
Follow-ups are done at different intervals depending on the diagnosis. As a rule, the biological samples are taken: 1. At diagnosis. 2. After the first tumor impact (surgery or treatment). 3. After any other form of tumor impact (surgery or treatment), or at a scheduled follow-up visit. 4. At the first recurrence, relapse or progression, or at a scheduled follow-up visit.
- Recruitment Target
-
- Individuals
- Number of Participants
- No Limit
- Number of Participants with Biological Samples
- No Limit
- Supplementary information about number of participants
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Each patient usually donates 3 sample types at inclusion (whole blood, serum, plasma), and 2 (serum, plasma) at each follow-up. Participants included until year 2021 was approximately 16000.
Samples collected until year 2021 was approximately 45000. - Supplementary Information
-
Patients are included in U-CAN after signing a written informed consent form.
Marker Papers
Glimelius B, Melin B, Enblad G, et al. U-CAN: a prospective longitudinal collection of biomaterials and clinical information from adult cancer patients in Sweden. Acta Oncol. 2018; 57(2):187-194.
PUBMED 28631533Supplementary Information
The U-CAN-project is continously including participants and collecting biological samples.
Questionnaire
Timeline
Population
U-CAN population
The population consist of men and women diagnosed with any of the 14 selected cancer types, living primarily in the counties of Uppsala and Västerbotten or that have been referred to the two university hospitals for diagnosis, treatment and/or follow-up from surrounding counties.
Selection Criteria
- Countries
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- Sweden
- Territory
- Uppsala, Umeå
- Health Status
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- Individuals diagnosed with any of the diseases that U-CAN collects.
Sources of Recruitment
- Specific Population
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- Clinic patients
Sample Size
- Number of Participants
- No Limit
- Supplementary information about number of participants
-
Number of participants included until year 2021 was approximately:
Uppsala, n = 16000
Umeå, n = 7700
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | U-CAN - Baseline |
|
|
2010 (June) | Ongoing |
| 1 | U-CAN - Follow-up 1 |
|
|
2010 (June) | Ongoing |
| 2 | U-CAN - Follow-up 2 |
|
|
2010 (June) | Ongoing |
| 3 | U-CAN - Follow-up 3 |
|
|
2010 (June) | Ongoing |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2023-08-10T18:19:00.870