Study for Evaluation of Newly Onset Chest Pain and Rapid Diagnosis of Myocardial Necrosis
The primary objective of the study was the improvement of early diagnosis of myocardial infarction by clinical variables and biomarkers.
Overview
- Acronym
- stenoCARDIA
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2007 - 2009
- General Information on Follow Up (profile, frequency)
-
Patients with suspected myocardial infarction are assessed upon admission to chest pain unit, as well as 3 and 6 hours after admission.
- Recruitment Target
-
- Individuals
- Number of Participants
- 1,800
- Number of Participants with Biological Samples
- 1,800
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
- By contacting the study representative: Dr. Tanja Zeller (University Heart and Vascular Center Hamburg)
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
| Can leave the study facility | ||
| Can leave the country |
Cost
| Possible Access to Data | Variable Cost |
| Possible Access to Biosamples | Variable Cost |
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
Access only upon submission of project-specific proposal and approval by Access committee of the study. Study specific contract is required.
Marker Paper
Keller T, Zeller T, Peetz D, et al. Sensitive troponin I assay in early diagnosis of acute myocardial infarction. New England Journal of Medicine, 2009; 361(9): 868–877.
PUBMED 19710485Supplementary Information
https://clinicaltrials.gov/ct2/show/NCT03227159
Timeline
Population
StenoCARDIA population
The population is composed of patients with suspected Acute Myocardial Infarction (AMI) between 18 and 85 years old, presenting to participating emergency departments within 24 hours of the onset of chest pain.
Selection Criteria
- Minimum age
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18
- Maximum age
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85
- Countries
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- Germany
- Territory
- Mainz, Koblenz and Hamburg
- Health Status
-
- Inclusions:
- Patients with chest discomfort within last 24 hours and suspected acute coronary syndrome are included in the study.
- Patients experiencing at least 30 minutes of chest discomfort or other symptoms consistent with possible acute coronary syndrome may also be included.
- Exlcusions:
- Inpatient in the hospital prior to onset of symptoms.
- Obvious traumatic disease.
- Patients with cardiogenic shock.
- Other Criteria
-
- Exlcusions:
- Major surgery within last 4 weeks.
- Other significant laboratory abnormalities that the investigator feels may compromise the patient's safety by participation in the study.
- Women who are pregnant or breast feeding.
- Obvious IV drug abuse.
- Refusal to provide written informed consent.
Sources of Recruitment
- Specific Population
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- Clinic patients
- Supplementary Information
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Patients were recruited from the chest pain units of the 3 German study centers: Johannes Gutenberg-University Medical Center Mainz, Federal Armed Forces Hospital Koblenz, and University Hospital Hamburg-Eppendorf.
Sample Size
- Number of Participants
- 1,800
- Number of Participants with Biological Samples
- 1,800
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | StenoCARDIA - Enrollment |
|
|
2007 (January) | 2009 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
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Last Update: 2023-08-10T18:18:35.634