Long-term outcomes following COVID-19 in Pediatrics
The primary objective of the Long-term outcomes following COVID-19 in Pediatrics study is to determine the long-term healthcare resource utilization and health care costs among pediatric survivors of COVID-19 infection.
The second objective of this study is to describe and compare the hospitalization characteristics, longitudinal health care utilization, mortality and risk of long-term sequalae between children hospitalized for COVID-19 infections and children hospitalized for other respiratory infections.
Overview
- Acronym
- POPCORN-LTO
- Website
- POPCORN-LTO
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2020 - 2024
- General Information on Follow Up (profile, frequency)
-
Participants are followed up 1 to 3 times after the baseline assessment.
- Recruitment Target
-
- Individuals
- Number of Participants
- No Limit
- Supplementary Information
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This study uses administrative health data that do not have any patient identifiers. Data for this study will be provided by the Canadian Institute for Health Information (CIHI), which contains the National Ambulatory Care Reporting System database (NACRS) and the Discharge Abstract Database (DAD) for all provinces except Quebec. A two-year lookback window from index hospital admission will be used to ascertain for baseline medical complexity of the participant.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
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Timeline
Populations
POPCORN-LTO - COVID Cohort
The population is composed of children and youth aged 18 years or younger living in any province and territories of Canada who were infected with COVID-19 and were hospitalized for their infection.
Selection Criteria
- Maximum age
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18
- Countries
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- Canada
- Canadian Provinces
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- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Health Status
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- Participants hospitalized for COVID-19 are identified using the following codes listed as the Most Responsible Diagnosis (MRDx) for their hospital encounter: * U07.1 for confirmed COVID-19 or * U07.2 for suspected COVID-19 or * U07.3 for Multisystem inflammatory syndrome associated with COVID-19 (MIS-C)
Sources of Recruitment
- Specific Population
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- Clinic patients
- Supplementary Information
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Participants are identified from the Canadian Institute for Health Information (CIHI) databases such as National Ambulatory Care Reporting System database (NACRS) and Discharge Abstract Database (DAD). Participants from Québec are exclusively identified from the Institute National d’Excellence en Santé et Services Sociaux (INESSS).
Sample Size
- Number of Participants
- No Limit
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | POPCORN-LTO - COVID Cohort - Baseline |
|
2020 (April) | 2023 (March) | |
| 1 | POPCORN-LTO - COVID Cohort - Follow-up |
|
2023 (April) | 2024 (March) |
POPCORN-LTO - Matched Cohort
The population is composed of children aged 18 years old or younger living in any province and territories of Canada who were hospitalized for a non-COVID-19 infection affecting the upper or lower respiratory tract.
Selection Criteria
- Maximum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Health Status
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- Participants must have been hospitalized and their "Most Responsible Diagnosis" (MRDx) must be an upper or lower respiratory tract infection, such as: * Influenza, parainfluenza * RSV bronchiolitis * Pneumonia * Croup * Infection associated with rhinovirus * Human metapneumovirus * Enterovirus * Other non-COVID-19 coronaviruses
- Supplementary Information about selection criteria
-
Participants are selected to match the COVID cohort based on the following characteristics: * Sex * Month/year of hospitalization (to account for COVID waves) * Province * Deprivation quintile
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are identified from the Canadian Institute for Health Information (CIHI) databases such as National Ambulatory Care Reporting System database (NACRS) and Discharge Abstract Database (DAD). Participants from Québec are exclusively identified from the Institute National d’Excellence en Santé et Services Sociaux (INESSS).
Sample Size
- Number of Participants
- No Limit
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | POPCORN-LTO - Matched Cohort - Baseline |
|
2020 (April) | 2023 (March) | |
| 1 | POPCORN-LTO - Matched Cohort - Follow-up |
|
2023 (April) | 2024 (March) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
|---|
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-08-16T14:10:07.659