LifeGene Project
The objective of LifeGene is to develop a prospective, population-based cohort that is a resource for research in biomedicine as well as behavioural and social sciences. Study features include:
- Ascertaining a cohort of at least 100,000 Swedes, including households;
- Repeated assessment of in depth exposure and outcome information through electronic means;
- Linkage with all available sources of medical record information (inpatient registry, cancer registry, and when possible, through primary care records);
- Collection of DNA and serum/plasma from all members of the cohort at initiation;
- Collection of other tissues (whole blood, serum/plasma, CSF, skin biopsies, etc.) as specific research questions dictate.
Overview
- Acronym
- LifeGene
- Website
- LifeGene
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2009 -
- General Information on Follow Up (profile, frequency)
-
Following baseline, participants and their family are prompted annually to respond a short, web-based questionnaire.
- Recruitment Target
-
- Individuals
- Families
- Number of Participants
- 100,000
- Number of Participants with Biological Samples
- 50,000
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Almqvist C, Adami HO, Franks PW, Groop L, Ingelsson E, Kere J, Lissner L, Litton JE, Maeurer M, Michaëlsson K, Palmgren J, Pershagen G, Ploner A, Sullivan PF, Tybring G, Pedersen NL. LifeGene--a large prospective population-based study of global relevance. European Journal of Epidemiology. 2011; 26(1): 67-77.
PUBMED 21104112Timeline
Populations
LifeGene - Adults
Index participants recruited to the study are Swedish men and women, aged 18 to 50 years at the time of recruitment. These participants in turn may invite family members. Adults of any age may volunteer. Hence the age range is 0-95.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Sweden
- Supplementary Information about selection criteria
-
The minimum age is for index participants, who in turn may invite family/members of their household, including children 0-18 years. Adults of any age may participate, however initial focus was on ages 18-50.
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Selected sample
- Supplementary Information
-
Index participants were randomly sampled from the general population from the supplier of addresses; SPAR or Skatteverket. Other persons interested in participating have the possibility to spontaneously register from the LifeGene website.
Sample Size
- Number of Participants
- 100,000
- Number of Participants with Biological Samples
- 50,000
- Supplementary information about number of participants
-
The number of participants is continuing to be accrued.
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | LifeGene - Adults - Baseline |
|
|
2009 (September) | 2016 (December) |
| 1 | LifeGene - Adults - Follow-up 1 |
|
2010 (November) | 2016 (December) | |
| 2 | LifeGene - Adults - Follow-up 2 |
|
2011 (November) | 2016 (December) | |
| 3 | LifeGene - Adults - Follow-up 3 |
|
2013 (November) | 2016 (December) | |
| 4 | LifeGene - Adults - Follow-up 4 |
|
2014 (November) | 2016 (December) |
LifeGene - Children
Participants are the children of the adults enrolled in the study.
Selection Criteria
- Maximum age
-
18
- Countries
-
- Sweden
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of the adults recruited
- Supplementary Information
-
These are the children of the adult participants.
Sample Size
- Number of Participants
- No Limit
- Supplementary information about number of participants
-
Collection is ongoing
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | LifeGene - Children - Baseline |
|
|
2009 (September) | 2016 (December) |
| 1 | LifeGene - Children - Follow-up 1 |
|
2011 (November) | 2016 (December) | |
| 2 | LifeGene - Children - Follow-up 2 |
|
2012 (November) | 2016 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2020-02-05T11:07:48.092