Trajectories of Healthy Life using Public Health and Primary Care Interventions in Canada
The objective of this study is to evaluate whether a technology-based intervention can improve the health of families before pregnancy, during pregnancy, and into early childhood and promote child development while preventing obesity and chronic diseases.
Overview
- Acronym
- HeLTI Canada
- Website
- HeLTI Canada
- Investigators
-
- Contacts
-
General Design
- Study design
- Clinical trial
- Start - End Year
- 2021 -
- General Information on Follow Up (profile, frequency)
-
After the baseline preconception collection, mothers and partners are followed up three times (at 12, 24, and 36 months if no pregnancy occurs) or once during pregnancy (24 to 28 weeks), and six times postpartum (at 3, 6, 12, 24, 36, 48, and 60 months). After 3 months postpartum, children and siblings are followed up five times (at 6, 12, 24, 36, 48, and 60 months).
- Recruitment Target
-
- Families
- Number of Participants
- 18,564
- Number of Participants with Biological Samples
- 18,564
- Supplementary information about number of participants
-
Mothers: 5230 participants
Partners: up to 5230 participants
Children: 3660 participants
Siblings: up to 4444 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Papers
Dennis CL, Marini F, Dick JA, et al. Protocol for a randomised trial evaluating a preconception-early childhood telephone-based intervention with tailored e-health resources for women and their partners to optimise growth and development among children in Canada: a Healthy Life Trajectory Initiative (HeLTI Canada). BMJ Open. 2021.11(2):e046311.
PUBMED 33568380Supplementary Information
More information on the HeLTI consortium is available at https://helti.org/
Timeline
Populations
HeLTI Canada - Mothers - Intervention
The population is composed of women who are planning to be pregnant within the next three years and are randomly allocated to the intervention group. In the intervention group, participants get detailed risk assessments, individualized and structured management plans, scheduled follow-up calls, and access to individualized and evidence-based online resources.
Selection Criteria
- Gender
-
Women only
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Health Status
-
- Women are excluded from this study if they have type I diabetes.
- Other Criteria
- Women are excluded from this study if pregnancy does not occur within three years of enrollment.
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited from social media such as Facebook and Google ads, obstetric and postpartum clinics, primary care practices, and community healthcare centers that provide postpartum and child care.
Sample Size
- Number of Participants
- 2,615
- Number of Participants with Biological Samples
- 2,615
Data Collection Events
HeLTI Canada - Mothers - Control
The population is composed of women who are planning to be pregnant within the next three years and are randomly allocated to the control group. The control group has access to the usual standard care but will not receive the study intervention. Participants also have an individualized webpage to access injury prevention and child safety e-health resources.
Selection Criteria
- Gender
-
Women only
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Health Status
-
- Women are excluded from this study if they have type I diabetes.
- Other Criteria
- Women are excluded from this study if pregnancy does not occur within three years of enrollment.
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited from social media such as Facebook and Google ads, obstetric and postpartum clinics, primary care practices, and community healthcare centers that provide postpartum and child care.
Sample Size
- Number of Participants
- 2,615
- Number of Participants with Biological Samples
- 2,615
Data Collection Events
HeLTI Canada - Partners - Intervention
The population is composed of the partners of participating women who are allocated to the intervention group. In the intervention group, participants get detailed risk assessments, individualized and structured management plans, scheduled follow-up calls, and access to individualized and evidence-based online resources.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Other Criteria
- Participants are excluded if their partner's pregnancy does not occur within three years of enrollment.
Sources of Recruitment
- Specific Population
-
- Other specific population : Partners of participating mothers.
Sample Size
- Number of Participants
- 2,615
- Number of Participants with Biological Samples
- 2,615
Data Collection Events
HeLTI Canada - Partners - Control
The population is composed of the partners of participating women who are allocated to the control group. The control group has access to the usual standard care but will not receive the study intervention. Participants also have an individualized webpage to access injury prevention and child safety e-health resources.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Other Criteria
- Participants are excluded if their partner's pregnancy does not occur within three years of enrollment.
Sources of Recruitment
- Specific Population
-
- Other specific population : Partners of participating mothers.
Sample Size
- Number of Participants
- 2,615
- Number of Participants with Biological Samples
- 2,615
Data Collection Events
HeLTI Canada - Children - Intervention
The population is composed of children of participating mothers, who are conceived after their mothers are randomized into the intervention group of the study. Children included in the study are born from a singleton birth or a twin birth if they are the firstborn child.
Selection Criteria
- Newborns
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Other Criteria
- Children included in the study are born from a singleton birth or a twin birth if they are the firstborn child.
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of participating mothers.
Sample Size
- Number of Participants
- 1,830
- Number of Participants with Biological Samples
- 1,830
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 1 | HeLTI Canada - Children Intervention - 3 months postpartum |
|
|
2022 | 2027 |
| 2 | HeLTI Canada - Children Intervention - 6 months postpartum |
|
2022 | 2028 | |
| 3 | HeLTI Canada - Children Intervention - 12 months postpartum |
|
2022 | 2028 | |
| 4 | HeLTI Canada - Children Intervention - 24 months postpartum |
|
2023 | 2029 | |
| 5 | HeLTI Canada - Children Intervention - 36 months postpartum |
|
2024 | 2030 | |
| 6 | HeLTI Canada - Children Intervention - 48 months postpartum |
|
2025 | 2031 | |
| 7 | HeLTI Canada - Children Intervention - 60 months postpartum |
|
|
2026 | 2032 |
HeLTI Canada - Children - Control
The population is composed of children of participating mothers, who are conceived after their mothers are randomized into the control group of the study. Children included in the study are born from a singleton birth or a twin birth if they are the firstborn child.
Selection Criteria
- Newborns
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
- Other Criteria
- Children included in the study are born from a singleton birth or a twin birth if they are the firstborn child.
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of participating mothers.
Sample Size
- Number of Participants
- 1,830
- Number of Participants with Biological Samples
- 1,830
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 1 | HeLTI Canada - Children Control - 3 months postpartum |
|
|
2022 | 2027 |
| 2 | HeLTI Canada - Children Control - 6 months postpartum |
|
2022 | 2028 | |
| 3 | HeLTI Canada - Children Control - 12 months postpartum |
|
2022 | 2028 | |
| 4 | HeLTI Canada - Children Control - 24 months postpartum |
|
2023 | 2029 | |
| 5 | HeLTI Canada - Children Control - 36 months postpartum |
|
2024 | 2030 | |
| 6 | HeLTI Canada - Children Control - 48 months postpartum |
|
2025 | 2031 | |
| 7 | HeLTI Canada - Children Control - 60 months postpartum |
|
|
2026 | 2032 |
HeLTI Canada - Siblings - Intervention
The population is composed of the children of participants age 5 or younger who are born before recruitment into the study. Their parents are participants in the intervention group.
Selection Criteria
- Maximum age
-
5
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of participants
- Supplementary Information
-
Children of the participants born before recruitment into the study.
Sample Size
- Number of Participants
- 2,222
- Number of Participants with Biological Samples
- 2,222
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | HeLTI Canada - Siblings Intervention - 3 months postpartum |
|
2021 | 2023 | |
| 1 | HeLTI Canada - Siblings Intervention - 6 months postpartum |
|
2021 | 2024 | |
| 2 | HeLTI Canada - Siblings Intervention - 12 months postpartum |
|
2021 | 2024 | |
| 3 | HeLTI Canada - Siblings Intervention - 24 months postpartum |
|
2021 | 2025 | |
| 4 | HeLTI Canada - Siblings Intervention - 36 months postpartum |
|
2021 | 2026 | |
| 5 | HeLTI Canada - Siblings Intervention - 48 months postpartum |
|
2021 | 2027 | |
| 6 | HeLTI Canada - Siblings Intervention - 60 months postpartum |
|
2021 | 2028 |
HeLTI Canada - Siblings - Control
The population is composed of the children of participants age 5 or younger who are born before recruitment into the study. Their parents are participants in the control group.
Selection Criteria
- Maximum age
-
5
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Manitoba
- New Brunswick
- Newfoundland and Labrador
- Northwest Territories
- Nova Scotia
- Nunavut
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Yukon
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of participants
- Supplementary Information
-
Children of the participants born before recruitment into the study.
Sample Size
- Number of Participants
- 2,222
- Number of Participants with Biological Samples
- 2,222
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | HeLTI Canada - Siblings Control - 3 months postpartum |
|
2021 | 2023 | |
| 1 | HeLTI Canada - Siblings Control - 6 months postpartum |
|
2021 | 2024 | |
| 2 | HeLTI Canada - Siblings Control - 12 months postpartum |
|
2021 | 2024 | |
| 3 | HeLTI Canada - Siblings Control - 24 months postpartum |
|
2021 | 2025 | |
| 4 | HeLTI Canada - Siblings Control - 36 months postpartum |
|
2021 | 2026 | |
| 5 | HeLTI Canada - Siblings Control - 48 months postpartum |
|
2021 | 2027 | |
| 6 | HeLTI Canada - Siblings Control - 60 months postpartum |
|
2021 | 2028 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2023-01-18T16:11:01.095