Hertfordshire Ageing Study
The principal objective of the HAS is to examine life course influences on healthy ageing. The outcomes of interest are sarcopenia, frailty, falls, physical performance and cognitive function. The main potential determinants of healthy ageing under investigation are intra-uterine and post-natal size and growth, genetic characteristics and adult physical activity, diet, lifestyle and socioeconomic status.
Overview
- Acronym
- HAS
- Website
- HAS
- Investigators
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- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 1920 -
- General Information on Follow Up (profile, frequency)
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The NHSCR was used to trace 6,803 men and women born in North Hertfordshire between 1920 and 1930, for whom birth and infancy data had been recorded. The NHSCR identified 2,621 men and women as resident in the UK in 1994; 1,428 of these were still resident in North Hertfordshire. With permission from their GP, we invited these men and women to participate in a home interview and clinic at which a wide panel of markers of ageing were characterised (including grip strength, cognitive function, anthropometry, visual acuity and lens opacity, hearing threshold and skin thickness). This first HAS follow-up was conducted between 1994 and 1995 when the participants ranged in age from 63 to 73 years. A second follow-up was conducted in 2003-05, a median of 9 years after the first follow-up, when participants were aged 72-83 years.
- Recruitment Target
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- Individuals
- Number of Participants
- 1,428
- Number of Participants with Biological Samples
- 717
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
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Marker Paper
Syddall HE, Simmonds SJ, Martin HJ, Watson C, Dennison EM, Cooper C, Sayer AA; Hertfordshire Cohort Study Group. Cohort profile: The Hertfordshire Ageing Study (HAS). Int J Epidemiol. 2010 Feb;39(1):36-43. doi: 10.1093/ije/dyn275.
PUBMED 19131391Timeline
Population
The HAS population consists of 1,428 live singleton births in North Hertfordshire between 1920 and 1930.
Selection Criteria
- Newborns
- Countries
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- United Kingdom
- Territory
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North Hertfordshire
Sources of Recruitment
- General Population
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- Selected sample
Sample Size
- Number of Participants
- 1,428
- Number of Participants with Biological Samples
- 717
- Supplementary information about number of participants
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Baseline: 1428 individuals
Follow-up 1: Target population: 1428 individuals residing in North Hertfordshire: 824 participants for the interview of which 717 with biological samples.
Follow-up 2: Target population: 717 individuals with biological samples from follow-up 1: 359 participants for the interview of which 294 with biological samples.
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | HAS - Baseline |
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1920 | 1930 | |
| 1 | HAS - Follow-up 1 |
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1994 | 1995 |
| 2 | HAS - Follow-up 2 |
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|
2003 | 2005 |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
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Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
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