European Prospective Investigation into Cancer and Nutrition - Oxford
EPIC is a multi-centre prospective cohort based on healthy, middle-aged subjects who agree, following an active invitation, to participate in the study and to have their health status followed-up for the rest of their lives. The study is based in ten European countries and includes populations characterized by large variations in dietary habits and cancer risk.
The EPIC study aims to investigate the relationships between diet, nutritional status, lifestyle and environmental factors, and the incidence of cancer and other chronic diseases.
The main objective of the The Oxford component of the European Prospective Investigation is to examine how diet influences the risk of cancer, particularly for the most common types of cancer in Britain, as well as other chronic diseases. The study began in 1993 and since then, a great deal of important research, from both EPIC-Oxford and its collaboration with other centres in Europe, has been published.
Overview
- Acronym
- EPIC - Oxford
- Website
- EPIC - Oxford
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 1993 -
- General Information on Follow Up (profile, frequency)
-
Participants were assessed at baseline between 1993 and 1999. They were then followed up in 2002, 2007 and 2010.
- Recruitment Target
-
- Individuals
- Number of Participants
- 65,429
- Number of Participants with Biological Samples
- 19,500
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Crowe FL, Appleby PN, Allen NE, Key TJ. Diet and risk of diverticular disease in Oxford cohort of European Prospective Investigation into Cancer and Nutrition (EPIC): prospective study of British vegetarians and non-vegetarians. BMJ. 2011; 343: d4131.
PUBMED 21771850Timeline
Populations
The population is composed of men and women aged 35 years and older on the collaborating general practitioners’ lists in Greater Manchester, Oxfordshire and Buckinghamshire.
Selection Criteria
- Minimum age
-
35
- Countries
-
- United Kingdom
- Territory
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Oxfordshire, Buckinghamshire and Greater Manchester.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
The participants were recruited from the general practitioners' lists'.
Sample Size
- Number of Participants
- 43,993
- Number of Participants with Biological Samples
- 43,993
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EPIC-Oxford - Baseline assessment |
|
|
1993 | 1999 |
| 1 | EPIC-Oxford - First 7-day food diary |
|
2002 | 2003 | |
| 2 | EPIC-Oxford - First follow-up questionnaire |
|
2002 | 2003 | |
| 3 | EPIC-Oxford - Second 7-day food diary |
|
2007 | 2008 | |
| 4 | EPIC-Oxford - Second follow-up questionnaire |
|
2007 | 2008 | |
| 5 | EPIC-Oxford - Third follow-up questionnaire |
|
2010 | 2010 |
The population is composed of vegetarians and vegans, aged 20 years and older, members of the Vegetarian Society of the UK, the Vegan Society and all participants from the Oxford Vegetarian Study.
Selection Criteria
- Minimum age
-
20
- Countries
-
- United Kingdom
- Territory
-
England, Scotland, Wales, Northen Ireland
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Members of an association
- Supplementary Information
-
The participants were recruited from the members of the Vegetarian Society of the UK, the Vegan Society, and previous participants in the Oxford Vegetarian Study, and through other health related magazines and health food shops.
Sample Size
- Number of Participants
- 21,436
- Number of Participants with Biological Samples
- 21,436
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EPIC-Oxford - Baseline assessment |
|
|
1993 | 1999 |
| 1 | EPIC-Oxford - First 7-day food diary |
|
2002 | 2003 | |
| 2 | EPIC-Oxford - First follow-up questionnaire |
|
2002 | 2003 | |
| 3 | EPIC-Oxford - Second 7-day food diary |
|
2007 | 2008 | |
| 4 | EPIC-Oxford - Second follow-up questionnaire |
|
2007 | 2008 | |
| 5 | EPIC-Oxford - Third follow-up questionnaire |
|
2010 | 2010 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|