Cardiovascular Health Study
The main objective of the study is to identify factors related to the onset of coronary heart disease and stroke. CHS is designed to determine the importance of conventional cardiovascular disease (CVD) risk factors in older adults, and to identify new risk factors in this age group, especially those that may be protective and modifiable. Other objectives are the following:
- To quantify associations of conventional and hypothesized risk factors with CHD and stroke.
- To assess the association of indicators of subclinical disease, identified by noninvasive measures such as carotid ultrasonography and echocardiography, with incidence of CHD and stroke.
- To quantify the association of conventional and hypothesized risk factors with subclinical disease.
- To characterize the natural history of CHD and stroke, and identify factors associated with clinical course.
- To describe the prevalence and distributions of risk factors, subclinical disease, and clinically diagnosed CHD and stroke.
Overview
- Acronym
- CHS
- Website
- CHS
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 1987 -
- General Information on Follow Up (profile, frequency)
-
Between enrollment and 1999, participants were seen in the clinic annually, and contacted by phone at 6-month intervals to collect information about hospitalizations and potential cardiovascular events. Since 1999, participants have been contacted every 6 months by phone, primarily to ascertain health status for events follow-up.
- Recruitment Target
-
- Individuals
- Number of Participants
- 5,888
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Fried LP, Borhani NO, Enright P, Furberg CD, Gardin JM, Kronmal RA, Kuller LH, Manolio TA, Mittelmark MB, Newman A, et al. The Cardiovascular Health Study: design and rationale. Annals of epidemiology, 1991; 1(3): 263-76.
PUBMED 1669507Timeline
Population
CHS Population
The CHS population is composed of men and women aged 65 years and older and living in four selected communities (Forsyth County, North Carolina; Sacramento County, California; Washington County, Maryland; and Pittsburgh, Pennsylvania).]
Selection Criteria
- Minimum age
-
65
- Countries
-
- United States of America
- Territory
-
Forsyth County, North Carolina; Sacramento County, California; Washington County, Maryland; and Pittsburgh, Pennsylvania.
- Other Criteria
- Participants had to be noninstitutionalized, expecting to remain in the area for the next three years, and able to give consent and not requiring a proxy respondent at baseline. Potentially eligible individuals who were wheelchair-bound in the home at baseline or were receiving hospice treatment, radiation therapy or chemotherapy for cancer were excluded.
- Supplementary Information about selection criteria
-
Between November 1992 and June 1993, an additional 687 African Americans were recruited using similar methods.
Sources of Recruitment
- Specific Population
-
- Other specific population : Medicare eligibility lists of the Health Care Financing Administration (HCFA)
- Supplementary Information
-
Participants were sampled from Medicare eligibility lists of the Health Care Financing Administration (HCFA).
Sample Size
- Number of Participants
- 5,888
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CHS - Baseline examination |
|
|
1989 (June) | 1990 (June) |
| 1 | CHS - Interim telephone calls |
|
1990 (December) | 2015 (December) | |
| 2 | CHS - Yearly examination |
|
|
1992 (January) | 1999 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2023-08-10T18:18:39.690