Canadian COVID-19 Cohort Study: Study of the Epidemiology of COVID-19 in Canadian Healthcare Workers
The primary objectives of this study are to:
* Identify workplace (e.g., exposure to patients), community (e.g., rate of positive COVID tests), household (e.g., household crowding index), and personal (e.g., adherence to protective practices) risk factors for COVID-19 in HCWs;
* Assess whether one or more of three categories of putatively higher risk acute care hospital HCWs are indeed at higher risk of COVID-19 than other acute care hospital HCWs;
* Determine the incidence of symptomatic COVID-19 infection in HCWs;
* Estimate the incidence of asymptomatic COVID-19 infection in HCWs during the first pandemic season by measuring seroconversion to anti-SARS-CoV-2 antibodies; and
* Describe the intended and actual uptake of COVID-19 vaccines in HCWs.
Its secondary objectives are to:
* Determine the patterns of immune responses over time using dried blood spots (including post-vaccination); and
* Describe the psychological impact on HCWs during an outbreak of a novel respiratory virus.
Its exploratory objective is to:
1. Determine the incidence of reinfection,
2. Determine the effectiveness of the COVID-19 vaccine(s).
Overview
- Acronym
- CCCS
- Website
- CCCS
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2020 - 2022
- General Information on Follow Up (profile, frequency)
-
After enrollment, participants are followed-up for 12 months with weekly reports, testing/illness reports, and periodic blood samples collection. Blood samples are collected at enrolment, following vaccination against COVID, after a positive respiratory test (PCR), and every 6 months thereafter to assess antibody levels.
- Recruitment Target
-
- Individuals
- Number of Participants
- 2,460
- Number of Participants with Biological Samples
- 2,460
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Timeline
Population
CCCS population
The population is composed of 18 to 75 years old health care workers from acute care, rehabilitation, and complex care hospitals in Canada.
Selection Criteria
- Minimum age
-
18
- Maximum age
-
75
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Nova Scotia
- Ontario
- Quebec
- Other Criteria
-
Inclusion:
Occupation full- or part-time (>20 hours per week for health care workers, ≥ 8 hours per week for physician, nurse practitioner or midwife);
Have convenient access to and basic skills for use of computer or cell phone with internet capability;
Able to read and write English or French and available for follow-up during the study period.Exclusion: HCWs are not eligible if they plan to take leave from work for more than two consecutive weeks within the first 3 months of enrolment (e.g., vacation, maternity or medical leave, retirement).
Sources of Recruitment
- Specific Population
-
- Other specific population : Health care workers
- Supplementary Information
-
- Recruitment procedures included:
- a) sending email “blasts” to hospital employees,
- b) providing short videoconference or phone presentations for team meetings/huddles,
- c) posting electronic advertisements on internal hospital communications,
- d) displaying physical posters in staff work areas,
- e) advertising on social media platforms (e.g., Twitter or Facebook), and
- f) distributing pamphlets to targeted internal mailboxes.
Sample Size
- Number of Participants
- 2,460
- Number of Participants with Biological Samples
- 2,460
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CCCS - Baseline |
|
|
2020 | 2021 |
| 1 | CCCS - Longitudinal Follow-up |
|
2021 | 2022 | |
| 2 | CCCS - 6-month Follow-up |
|
|
2021 | 2022 |
| 3 | CCCS - 12-month Follow-up |
|
|
2022 | 2022 |
| 4 | CCCS - Daily report |
|
|
2021 | 2022 |
| 5 | CCCS - COVID-19 Vaccination |
|
|
2021 | 2022 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-02-27T06:27:11.625