Atherosclerosis Risk in Communities Study
ARIC is designed to investigate the etiology and natural history of atherosclerosis, the etiology of clinical atherosclerotic diseases, and variation in cardiovascular risk factors, medical care and disease by race, gender, location, and date. The objectives of the study are:
- Examine the ARIC cohort to characterize heart failure stages in the community, identify genetic and environmental factors leading to ventricular dysfunction and vascular stiffness, and assess longitudinal changes in pulmonary function and identify determinants of its decline;
- Cohort follow-up for cardiovascular events, including CHD, heart failure, stroke, and atrial fibrillation, and for the study risk factors related to progression of subclinical to clinical CVD;
- Enhance the ARIC cohort study with cardiovascular outcomes research to assess quality and outcomes of medical care for heart failure and heart failure risk factors;
- Community surveillance to monitor long-term trends in hospitalized MI, CHD deaths, and heart failure (inpatient and outpatient);
- Provide a platform for ancillary studies, training for new investigators, and data sharing.
Overview
- Acronym
- ARIC
- Website
- ARIC
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 1987 -
- General Information on Follow Up (profile, frequency)
-
The participants were re-examined every 3 years with the first exam occurring in 1987-1989, the second in 1990-1992, the third in 1993-1995, the fourth in 1996-1998 and the fifth in 2011-2013.
Follow-up also occurred annually or semi-annually by telephone to maintain contact and to assess health status of the cohort.
- Recruitment Target
-
- Individuals
- Number of Participants
- 15,792
- Number of Participants with Biological Samples
- 15,264
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
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Marker Paper
The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. American Journal of Epidemiology, 1989; 129(4): 687-702.
PUBMED 2646917Timeline
Populations
The participants were aged 45 to 64 years at recruitment and are living in one of the four ARIC centers areas (Washington County, MD; Forsyth County, NC; Jackson, MS; and Minneapolis, MN).
Selection Criteria
- Minimum age
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45
- Maximum age
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64
- Countries
-
- United States of America
- Territory
- Washington County, Forsyth County, Jackson, and Minneapolis
Sources of Recruitment
- General Population
-
- Volunteer enrolment
Sample Size
- Number of Participants
- 15,792
- Number of Participants with Biological Samples
- 15,264
- Supplementary information about number of participants
-
Exam 1: 15 792 participants
Exam 2: 14 348 participants
Exam 3: 12 887 participants
Exam 4: 11 656 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | ARIC - Exam 1 |
|
|
1987 | 1989 |
| 1 | ARIC - Annual and semi-annual follow-up |
|
1987 | 2014 | |
| 2 | ARIC - Exam 2 |
|
|
1990 | 1992 |
| 3 | ARIC - Exam 3 |
|
|
1993 | 1995 |
| 4 | ARIC - Exam 4 |
|
|
1996 | 1998 |
| 5 | ARIC - Exam 5 |
|
|
2011 | 2013 |
The participants were aged 35 to 84 years at recruitment and are living in the four communities investigated (Washington County, MD; Forsyth County, NC; Jackson, MS; and Minneapolis, MN).
Selection Criteria
- Minimum age
-
35
- Maximum age
-
84
- Countries
-
- United States of America
- Territory
- Washington County, Forsyth County, Jackson, and Minneapolis
Sources of Recruitment
- General Population
-
- Volunteer enrolment
Sample Size
- Number of Participants
- 470,000
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | ARIC - Community Surveillance |
|
1987 | 2014 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
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Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|