All Our Families
All Our Families (AOF) is a community-based, longitudinal pregnancy cohort developed to investigate the relationships between the prenatal and early life periods and outcomes for infants, children and mothers. AOF spans pregnancy, birth and early postpartum through childhood, and therefore provides the unique opportunity to describe the relations between prenatal events and early life development and to examine key factors that influence child and mother well-being over time. Through recognition of the unique opportunity to continue to collect relevant life course information on a large cohort of families, the main objectives of AOF have evolved to include the following:
* Investigate maternal and infant outcomes during the perinatal period, with a particular emphasis on barriers and facilitators to accessing health care services in Calgary, Alberta;
* Examine biological and environmental determinants of adverse birth outcomes, specifically spontaneous preterm birth;
* Further investigate risk and protective factors for optimal child development, and to understand the trajectory and impact of poor maternal mental health over time.
Overview
- Acronym
- AOF
- Website
- AOF
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2008 -
- General Information on Follow Up (profile, frequency)
-
Since recruitment, mothers have completed two questionnaires during pregnancy (less than 25 weeks and 34 to 36 weeks gestation). Children and mothers were followed up when the children were 4 months, 1, 2, 3, 5, 8 and 12 to 14 years of age. Participants who agreed to be contacted for additional research were mailed a flood impact questionnaire in the autumn of 2013 and three COVID-19 impact questionnaires between May 2020 and January 2022.
- Recruitment Target
-
- Families
- Number of Participants
- 6,774
- Number of Participants with Biological Samples
- 3,261
- Supplementary information about number of participants
-
Mothers: 3387 participants
Children: 3387 participants - Supplementary Information
-
Starting from the COVID-19 questionnaire in 2020, youth participants may complete their own questionnaires if their mothers consent to it.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Contact the research study team to access data: allourfamilies@ucalgary.ca
- On the study website : https://ucalgary.ca/allourfamilies
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
| Can leave the study facility | ||
| Can leave the country |
Anonymized, encrypted, special couriered.
Cost
| Possible Access to Data | Not yet defined |
| Possible Access to Biosamples | Not yet defined |
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
Marker Papers
Tough SC, McDonald SW, Collisson BA, Graham SA, Kehler H, Kingston D, Benzies K. Cohort Profile: The All Our Babies pregnancy cohort (AOB). International Journal of Epidemiology. 2017 Feb 8. 1-13.
PUBMED 28180262McDonald SW, Lyon AW, Benzies KM, et al,. The All Our Babies pregnancy cohort: design, methods, and participant characteristics. BMC Pregnancy Childbirth. 2013;13 Suppl 1(Suppl 1):S2. doi: 10.1186/1471-2393-13-S1-S2. Epub 2013 Jan 31.
PUBMED 23445747Timeline
Populations
AOF - Mothers
The population is composed of pregnant women of at least 18 years of age, with a gestational age of less than 25 weeks, and receiving prenatal care in Calgary.
Selection Criteria
- Gender
-
Women only
- Minimum age
-
18
- Pregnant Women
-
- First trimester
- Second trimester
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Territory
- Calgary
- Other Criteria
- Women had to be less than 25 weeks pregnant at enrollment, and accessing prenatal care in Calgary in 2008 or 2009.
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Pregnant women were recruited from primary care offices, community posters and word of mouth, and through a city-wide single provider public health laboratory service.
Sample Size
- Number of Participants
- 3,387
- Number of Participants with Biological Samples
- 1,862
- Supplementary information about number of participants
-
24 weeks gestation: 3363 participants
36 weeks gestation: 3184 participants
4 months postpartum: 3058 participants
1 year postpartum: 1574 participants
2 years postpartum: 1596 participants
3 years postpartum: 1994 participants
Flood: 1917 participants
5 years: 1992 participants
8 years: 2074 participants
COVID-19 questionnaire 1: 1333 participants
COVID-19 questionnaire 2: 1361 participants
COVID-19 questionnaire 3: 1280 participants
12-14 years postpartum: 1529 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | AOF - Mothers - 24 weeks |
|
|
2008 (May) | 2010 (December) |
| 1 | AOF - Mothers - 36 weeks |
|
|
2008 (August) | 2011 (March) |
| 2 | AOF - Mothers - Birth |
|
2008 (August) | 2011 (October) | |
| 3 | AOF - Mothers - 4 months postpartum |
|
2008 (December) | 2012 (February) | |
| 4 | AOF - Mothers - 1 year postpartum |
|
2011 (June) | 2012 (October) | |
| 5 | AOF - Mothers - 2 years postpartum |
|
2011 (October) | 2013 (October) | |
| 6 | AOF - Mothers - 3 years postpartum |
|
2012 (April) | 2014 (October) | |
| 7 | AOF - Mothers - Flood questionnaire |
|
2013 (November) | 2013 (November) | |
| 8 | AOF - Mothers - 5 years postpartum |
|
2014 (April) | 2016 (October) | |
| 9 | AOF - Mothers - 8 years postpartum |
|
2017 (February) | 2019 (October) | |
| 10 | AOF - Mothers - COVID-19 questionnaire 1 |
|
2020 (May) | 2020 (July) | |
| 11 | AOF - Mothers - COVID-19 questionnaire 2 |
|
2021 (March) | 2021 (April) | |
| 12 | AOF - Mothers - COVID-19 questionnaire 3 |
|
2021 (November) | 2022 (January) | |
| 13 | AOF - Mothers - 12-14 years postpartum |
|
2023 (January) | 2023 (July) |
AOF - Children
The population is composed of the children of the women enrolled in the study.
Selection Criteria
- Newborns
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Territory
- Calgary
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of the women already recruited in the study.
Sample Size
- Number of Participants
- 3,058
- Number of Participants with Biological Samples
- 1,399
- Supplementary information about number of participants
-
4 months postpartum: 3039 participants
1 year postpartum: 2614 participants
2 years postpartum: 1596 participants
3 years postpartum: 1994 participants
5 years postpartum: 1992 participants
8years postpartum: 1333 participants
1st COVID-19: 893 participants
2nd COVID-19: 1045 participants
3rd COVID-19: 1034 participants
12-14 years postpartum: 1317 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | AOF - Children - Birth |
|
|
2008 (August) | 2011 (October) |
| 1 | AOF - Children - 4 months postpartum |
|
2008 (December) | 2012 (February) | |
| 2 | AOF - Children - 1 year postpartum |
|
2011 (June) | 2012 (October) | |
| 3 | AOF - Children - 2 years postpartum |
|
2011 (October) | 2013 (October) | |
| 4 | AOF - Children - 3 years postpartum |
|
2012 (April) | 2014 (October) | |
| 5 | AOF - Children - 5 years postpartum |
|
2014 (April) | 2016 (October) | |
| 6 | AOF - Children - 8 years postpartum |
|
2017 (February) | 2019 (October) | |
| 7 | AOF - Children - COVID-19 questionnaire 1 |
|
2020 (July) | 2020 (August) | |
| 8 | AOF - Children - COVID-19 questionnaire 2 |
|
2021 (March) | 2021 (April) | |
| 9 | AOF - Children - COVID-19 questionnaire 3 |
|
2021 (November) | 2022 (January) | |
| 10 | AOF - Children - 12-14 years postpartum |
|
2023 (January) | 2023 (July) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-06-03T04:40:59.704