Autoimmunity in Post-Acute COVID Syndrome
The objectives of this study are:
* To understand the exact impairment of the immune system in patients experiencing Post-acute COVID-19 Syndrome (PACS) and why these patients develop autoantibodies,
* To characterize the impact of these autoantibodies on the clinical symptoms of PACS, and, potentially, identify ways to modify this.
Overview
- Acronym
- AI-PACS
- Investigators
-
Dr. Sarah SvenningsenMcMaster University, Research Institute of St. Joe's Hamilton, Firestone Institute for Respiratory Health & Imaging Research Centre, St. Joseph's Healthcare Hamilton
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2021 -
- General Information on Follow Up (profile, frequency)
-
Participants are followed up after 6 month and after 1 year of the initial visit. There is a possibility of a year 2 follow-up.
- Recruitment Target
-
- Individuals
- Number of Participants
- 100
- Number of Participants with Biological Samples
- 100
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Timeline
Population
AI-PACS population
The population is composed of patients experiencing PACS in Ontario and British Columbia.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- British Columbia
- Ontario
- Health Status
-
- Participants who are experiencing PACS are included.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Recruitment were done via community referrals, or patient referrals, or referrals from support groups.
Sample Size
- Number of Participants
- 100
- Number of Participants with Biological Samples
- 100
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | AI-PACS - Visit 1 |
|
|
2021 (September) | Ongoing |
| 1 | AI-PACS - Visit 2 |
|
|
2022 (March) | Ongoing |
| 2 | AI-PACS - Visit 2 |
|
|
2022 (September) | Ongoing |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-02-26T16:36:46.040